Monoclonal antibody of filamentous phage pVIII protein and application thereof

The invention relates to the technical field of biomedicine, in particular to a filamentous phage pVIII protein monoclonal antibody and an application thereof. A heavy chain variable region of the filamentous bacteriophage pVIII protein monoclonal antibody provided by the invention has an amino acid...

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Bibliographische Detailangaben
Hauptverfasser: SHEN JIANZHONG, ZHANG SUXIA, WEN KAI, WANG ZHANHUI, SHI WEIMIN, YU XUEZHI, YUAN TING, GUO LIUCHUAN, YANG HUIJUAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of biomedicine, in particular to a filamentous phage pVIII protein monoclonal antibody and an application thereof. A heavy chain variable region of the filamentous bacteriophage pVIII protein monoclonal antibody provided by the invention has an amino acid sequence as shown in SEQ ID NO.1, and a light chain variable region of the filamentous bacteriophage pVIII protein monoclonal antibody has an amino acid sequence as shown in SEQ ID NO.3; or, the heavy chain variable region has the amino acid sequence as shown in SEQ ID NO.2, and the light chain variable region has the amino acid sequence as shown in SEQ ID NO.4. The monoclonal antibody provided by the invention has the advantages of single biological activity, high titer and high specificity, can efficiently and specifically bind and recognize the filamentous bacteriophage, and has important application value in filamentous bacteriophage recognition and bacteriophage display technologies. 本发明涉及生物医学技术领域,具体涉及丝状噬菌体pⅧ