DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND
It is found that a desired peptide compound/amide compound, wherein a protective group is eliminated and/or a resin for solid-phase synthesis is removed, is able to be produced without causing damage on the main chain by bringing a starting peptide compound/starting amide compound into contact with...
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| Format: | Patent |
| Sprache: | chi ; eng |
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| Zusammenfassung: | It is found that a desired peptide compound/amide compound, wherein a protective group is eliminated and/or a resin for solid-phase synthesis is removed, is able to be produced without causing damage on the main chain by bringing a starting peptide compound/starting amide compound into contact with a silylating agent.
本发明的发明人发现，可以通过使起始肽化合物/起始酰胺化合物与甲硅烷基化剂接触而在没有主链破坏的情况下生产所需的肽化合物/酰胺化合物，其中保护基已经被脱除和/或固相合成用树脂已经被脱除。 |
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