Tadalafil tablet mixture and preparation method thereof

The invention relates to a tadalafil tablet mixture and a preparation method thereof. The tadalafil tablet mixture is prepared from the following raw materials in parts by weight of 40-90 parts of tadalafil, 3-7 parts of an oil phase, 85-130 parts of a surfactant, 30-60 parts of a co-emulsifier, 150-250 parts of an inclusion material, 35-70 parts of a liquid solvent, 3-5 parts of a coating material, 60-130 parts of a carrier material, 20-80 parts of an adhesive, 400-600 parts of a filler, 80-120 parts of a disintegrating agent, 2-10 parts of a lubricant and 5-8 parts of a flow aid. The preparation method of the tadalafil tablet mixture comprises the following steps of preparation of a tadalafil microemulsion inclusion compound, preparation of a tadalafil liquid-solid compression compound, and tabletting. The tadalafil is prepared into the microemulsion inclusion and the liquid-solid compressed compound before tabletting, the solubility and bioavailability of the tadalafil are improved, the stability of the me