Construction method for physiological abundance range of N-glycopeptide of healthy people and application of construction method

The invention provides a construction method for a physiological abundance range of N-glycopeptide of healthy people, and provides a method for screening potential markers of abnormal N-glycopeptide of diseases on the basis of the constructed physiological abundance range of N-glycopeptide of health...

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Hauptverfasser: SHANG SHITING, QIN WEIJIE, DONG HANGYAN, LI YUANYUAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a construction method for a physiological abundance range of N-glycopeptide of healthy people, and provides a method for screening potential markers of abnormal N-glycopeptide of diseases on the basis of the constructed physiological abundance range of N-glycopeptide of healthy people. The invention and the construction of the physiological abundance range of the urine N-glycopeptide provide a new method and thought for function and mechanism research and clinical biomarker screening based on urine glycoproteomics. 本发明提供了一种构建健康人群N-糖肽生理丰度范围的方法,并提供了基于构建的健康人群N-糖肽生理丰度范围筛选疾病异常N-糖肽潜在标志物的方法。本发明以及尿液N-糖肽生理丰度范围的构建,为基于尿液糖蛋白质组学的功能与机制研究和临床生物标志物筛选提供了新的方法与思路。