Dammarane tetracyclic triterpene compound and anti-gout application thereof

The invention relates to a cyclocarya paliurus extract, in particular to a cyclocarya paliurus dichloromethane active site and a dammarane tetracyclic triterpenoid compound as well as an extraction method and application thereof. The structure of the cyclodammarane tetracyclic triterpenoid compound...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ZENG HONGLIANG, CHEN ZUHUI, LIU YIQIAN, ZHU HUI, WU JIANPING, XU KANGPING, CHENG FEI, WANG YUYAN, OU SAIYU, LI GUIHUA, WEI XIFAN, HE XIAO'AI, GUI RUI
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to a cyclocarya paliurus extract, in particular to a cyclocarya paliurus dichloromethane active site and a dammarane tetracyclic triterpenoid compound as well as an extraction method and application thereof. The structure of the cyclodammarane tetracyclic triterpenoid compound is shown as a formula I or a formula II. The dammarane tetracyclic triterpenoid compound 1-26 and the dichloromethane active part of cyclocarya paliurus have good effects in preparation of activity tests for improving gout and reducing uric acid, and are expected to become a new generation of medicines for improving gout and reducing uric acid. 本发明涉及青钱柳的提取物,尤其涉及青钱柳二氯甲烷活性部位和达玛烷型四环三萜化合物及其提取方法以及应用。所述环达玛烷型四环三萜化合物,其结构如式Ⅰ或式Ⅱ所示:所述达玛烷型四环三萜化合物1-26和青钱柳二氯甲烷活性部位在制备改善痛风和降尿酸的活性测试中取得了较好的效果,有望成为新一代改善痛风和降尿酸的药物。