Oxiconazole nitrate emulsifiable paste preparation and production method thereof

The invention provides an oxiconazole nitrate emulsifiable paste preparation and a production method thereof. The oxiconazole nitrate emulsifiable paste preparation provided by the invention is prepared from the following components in percentage by mass: 1.15% of oxiconazole nitrate, 12.00% of octadecanol, 4.50% of hexadecanol, 15.00% of white vaseline, 2.33% of bletilla striata powder, 0.20% of benzoic acid, 5.00% of polysorbate-60, 11.50% of propylene glycol and 48.32% of purified water. The oxiconazole nitrate emulsifiable paste preparation provided by the invention is good in stability, and the drug effect is not influenced after the oxiconazole nitrate emulsifiable paste preparation is placed for a long time; and the oxiconazole nitrate emulsifiable paste preparation has good film-forming property, is easy to coat and has less skin irritation. 本发明提供了一种硝酸奥昔康唑乳膏制剂及其生产方法。本发明提供的硝酸奥昔康唑乳膏制剂包括以下质量百分含量的组分：硝酸奥昔康唑1.15％，十八醇12.00％，十六醇4.50％，白凡士林15.00％，白芨粉2.33％，苯甲酸0.20％，聚山梨酯-605.00％，丙二醇11.50％和纯化水48.32％。本发明提供的硝酸奥昔康唑乳膏