Plugging method for high-permeability layer water breakthrough oil well

The invention belongs to the technical field of oil exploitation, and particularly relates to a plugging method for a high-permeability layer water breakthrough oil well. The plugging method comprises the following steps that active water, a nanoscale plugging agent and a micron-sized plugging agent are prepared, and the prepared active water, a nanoscale plugging agent solution, a micron-sized plugging agent solution, active water are sequentially pumped into the high-permeability layer water breakthrough oil well through a profile control pump in a small-displacement mode and replaced into the stratum. According to the plugging method, the original mode that a plugging agent is squeezed and injected through a cement truck is changed, the profile control pump is used for squeezing and injecting different types of plugging materials as slugs to the deep part of a high-permeability zone under the small displacement condition, the high-permeability zone is plugged in the deep part, the productivity of an oil we