Novel synthesis process of tetramethylguanidine

The invention belongs to the field of pharmaceutical chemicals, and particularly relates to a novel process for synthesizing a tetramethylguanidine product. The synthesis process of tetramethylguanidine comprises two main processes of chlorination reaction and condensation reaction, and the existing...

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Bibliographische Detailangaben
Hauptverfasser: SUN SHUZHENG, WANG KAIGUANG, YIN JINHUA
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention belongs to the field of pharmaceutical chemicals, and particularly relates to a novel process for synthesizing a tetramethylguanidine product. The synthesis process of tetramethylguanidine comprises two main processes of chlorination reaction and condensation reaction, and the existing production process is an intermittent production process and is produced in batches. In the reaction process, an organic solvent needs to be used for extraction and purification for many times. The preparation process is complicated, the yield is low, the requirement on production equipment is high, the cost is high, and the safety and environmental protection are poor. The intermittent production process of tetramethylguanidine is continuously transformed, so that the yield is increased, and the safety, environmental friendliness and intelligence of the production line are improved; besides, the continuous transformation of the tetramethylguanidine production process has important practical significance. 本发明属于医药化