ANTIBODIES BINDING TO CITRULLINATED HISTONE 2A AND/OR 4

The invention provides antibodies or binding fragments thereof directed against citrulline-containing epitopes. The antibodies or binding fragments thereof of the invention can be used in therapy, for example in the treatment or prevention of Neutrophil Extracellular Trap (NET)-associated pathologie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VAN ROSMALEN JOHANNES WILHELMUS GERARDUS, CHIRIVI RENATO GERADUS SILVANO, RAATS JOZEF MARIA HENDRIK
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides antibodies or binding fragments thereof directed against citrulline-containing epitopes. The antibodies or binding fragments thereof of the invention can be used in therapy, for example in the treatment or prevention of Neutrophil Extracellular Trap (NET)-associated pathologies. 本发明提供了针对含瓜氨酸表位的抗体或其结合片段。本发明所述的抗体或其结合片段可用于治疗,例如用于治疗或预防中性粒细胞胞外陷阱(NET)相关的病理。