Marker combination for intestinal microecology, auxiliary diagnosis model and application thereof

The invention discloses a marker combination for intestinal microecology, an auxiliary diagnosis model and application of the marker combination. The marker combination comprises the following microorganisms: Scardovia, ruminococcus (not named), Bilophila, Bacteroides , Gemeria , Alistipes, Oxalobac...

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Hauptverfasser: MAO LIANGWEI, WANG PUQING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a marker combination for intestinal microecology, an auxiliary diagnosis model and application of the marker combination. The marker combination comprises the following microorganisms: Scardovia, ruminococcus (not named), Bilophila, Bacteroides , Gemeria , Alistipes, Oxalobacter, Solobacter, Bifidobacterium and Clostridiales (not named). The model provided by the invention can provide high-accuracy non-invasive Parkinson's disease auxiliary diagnosis, and the accuracy can reach 80.3%. 本发明公开了一种肠道微生态的标志物组合、辅助诊断模型及其应用。所述标志物组合包括以下微生物:斯卡多维亚菌属(Scardovia)、瘤胃菌属(未命名)(Ruminococcaceae noname)、嗜胆菌属(Bilophila)、拟杆菌属(Bacteroides)、孪生球菌属(Gemella)、另枝菌属(Alistipes)、草酸杆菌属(Oxalobacter)、索拉杆菌属(Solobacterium)、双歧杆菌属(Bifidobacterium)和梭菌属(未命名)(Clostridiales noname)。本发明的模型可以提供高准确率、无创的帕金森病辅助诊断,准确率可达80.3%。