Polyethylene glycol coupled drug as well as preparation method and application thereof

The invention relates to a polyethylene glycol coupled drug as well as a preparation method and application thereof, and in particular, relates to a polyethylene glycol coupled drug represented by a formula I or pharmaceutically acceptable salt thereof. The invention also relates to a preparation me...

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Bibliographische Detailangaben
Hauptverfasser:	DING XIAOLING, PENG YONGCHEN, GAO CHENGZHI, LIU MEI, LOU JIE, WANG YUANQIANG, LI GAOQUAN, YI YUYANG, YANG YUE, GAO JIA, CHEN HUIYU, WEI YUSONG, ZHANG QIAN, YANG XIANGWEI, LI DIEDIE, ZENG XIAFAN, HENG YANXIA, LI DAJUN, LIU LIWEI, LIU XI, TANG XIAO, WANG KAI, TU TAO, MEI GANG, LIU YUE, LUO QIANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The invention relates to a polyethylene glycol coupled drug as well as a preparation method and application thereof, and in particular, relates to a polyethylene glycol coupled drug represented by a formula I or pharmaceutically acceptable salt thereof. The invention also relates to a preparation method and an intermediate of the polyethylene glycol coupled drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the polyethylene glycol coupled drug or the pharmaceutically acceptable salt thereof, and an application of the pharmaceutical composition in preparation of drugs. 本发明涉及一种聚乙二醇偶联药物、其制备方法及用途，具体涉及如式I所示的聚乙二醇偶联药物或其药学上可接受的盐。本发明还涉及所述聚乙二醇偶联药物或其药学上可接受的盐的制备方法和中间体，包含所述聚乙二醇偶联药物或其药学上可接受的盐的药物组合物和在制备药物中的用途。