Meloxicam-containing injection and preparation method thereof
The invention relates to the field of pharmaceutical preparations, in particular to a meloxicam-containing injection which is composed of meloxicam, arginine and water, wherein the mass ratio of meloxicam to arginine is (4: 1)-(1: 10). According to the injection, by using the basic amino acid, the s...
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Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to the field of pharmaceutical preparations, in particular to a meloxicam-containing injection which is composed of meloxicam, arginine and water, wherein the mass ratio of meloxicam to arginine is (4: 1)-(1: 10). According to the injection, by using the basic amino acid, the solubility of the meloxicam is effectively improved under the condition that other solubilizers are not added, the prescription of the meloxicam solution is effectively improved, the preparation method of the meloxicam solution is simplified, the bioavailability of the medicine is further improved, and the treatment effect of the medicine is greatly improved.
本发明涉及医药制剂领域,涉及一种美洛昔康注射液,所述注射液由美洛昔康、精氨酸和水组成,所述美洛昔康与精氨酸的质量比为4:1~1:10。本发明注射液在碱性氨基酸的使用,实现了在不添加其他增溶剂的情况下有效提高美洛昔康的溶解性,有效改善了美洛昔康溶液的处方,简化了美洛昔康溶液的制备方法,并进一步提高了药物的生物利用度,极大的提高了药物的治疗效果。 |
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