Immune modifying particles for treatment of cancer
The present disclosure provides methods of treating cancer and proliferative diseases using immune-modifying particles in combination with cancer therapeutics, such as checkpoint inhibitors or biologic agents, to modify the activity of myeloid-derived suppressor cells (MDSCs), tumor-associated macro...
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| creator | PUISIS JOHN |
| description | The present disclosure provides methods of treating cancer and proliferative diseases using immune-modifying particles in combination with cancer therapeutics, such as checkpoint inhibitors or biologic agents, to modify the activity of myeloid-derived suppressor cells (MDSCs), tumor-associated macrophages (TAMs), neutrophils, monocytes, and/or tumor-associated stroma associated with promoting tumor growth and metastasis.
本公开提供了使用免疫修饰粒子与诸如检查点抑制剂或生物剂等癌症治疗剂的组合来改变与促进肿瘤生长和转移相关的髓源性抑制细胞(MDSC)、肿瘤相关巨噬细胞(TAM)、嗜中性粒细胞、单核细胞和/或肿瘤相关基质的活性从而治疗癌症和增生性疾病的方法。 |
| format | Patent |
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本公开提供了使用免疫修饰粒子与诸如检查点抑制剂或生物剂等癌症治疗剂的组合来改变与促进肿瘤生长和转移相关的髓源性抑制细胞(MDSC)、肿瘤相关巨噬细胞(TAM)、嗜中性粒细胞、单核细胞和/或肿瘤相关基质的活性从而治疗癌症和增生性疾病的方法。</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210518&DB=EPODOC&CC=CN&NR=112823001A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210518&DB=EPODOC&CC=CN&NR=112823001A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PUISIS JOHN</creatorcontrib><title>Immune modifying particles for treatment of cancer</title><description>The present disclosure provides methods of treating cancer and proliferative diseases using immune-modifying particles in combination with cancer therapeutics, such as checkpoint inhibitors or biologic agents, to modify the activity of myeloid-derived suppressor cells (MDSCs), tumor-associated macrophages (TAMs), neutrophils, monocytes, and/or tumor-associated stroma associated with promoting tumor growth and metastasis.
本公开提供了使用免疫修饰粒子与诸如检查点抑制剂或生物剂等癌症治疗剂的组合来改变与促进肿瘤生长和转移相关的髓源性抑制细胞(MDSC)、肿瘤相关巨噬细胞(TAM)、嗜中性粒细胞、单核细胞和/或肿瘤相关基质的活性从而治疗癌症和增生性疾病的方法。</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDDyzM0tzUtVyM1PyUyrzMxLVyhILCrJTM5JLVZIyy9SKClKTSzJTc0rUchPU0hOzEtOLeJhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoaGRhZGxgYGho7GxKgBANodLBE</recordid><startdate>20210518</startdate><enddate>20210518</enddate><creator>PUISIS JOHN</creator><scope>EVB</scope></search><sort><creationdate>20210518</creationdate><title>Immune modifying particles for treatment of cancer</title><author>PUISIS JOHN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN112823001A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2021</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>PUISIS JOHN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PUISIS JOHN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Immune modifying particles for treatment of cancer</title><date>2021-05-18</date><risdate>2021</risdate><abstract>The present disclosure provides methods of treating cancer and proliferative diseases using immune-modifying particles in combination with cancer therapeutics, such as checkpoint inhibitors or biologic agents, to modify the activity of myeloid-derived suppressor cells (MDSCs), tumor-associated macrophages (TAMs), neutrophils, monocytes, and/or tumor-associated stroma associated with promoting tumor growth and metastasis.
本公开提供了使用免疫修饰粒子与诸如检查点抑制剂或生物剂等癌症治疗剂的组合来改变与促进肿瘤生长和转移相关的髓源性抑制细胞(MDSC)、肿瘤相关巨噬细胞(TAM)、嗜中性粒细胞、单核细胞和/或肿瘤相关基质的活性从而治疗癌症和增生性疾病的方法。</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Immune modifying particles for treatment of cancer |
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