INHALABLE FORMULATION OF A SOLUTION CONTAINING FORMOTEROL FUMARATE AND ACLIDINIUM BROMIDE

The present invention discloses a liquid, propellant-free pharmaceutical formulation and a method for administering a pharmaceutical preparation by nebulizing the pharmaceutical preparation in an inhaler. The propellant-free pharmaceutical formulation comprising: (a) active substances selected from...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHANG HAILONG, HUANG CAIGU
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention discloses a liquid, propellant-free pharmaceutical formulation and a method for administering a pharmaceutical preparation by nebulizing the pharmaceutical preparation in an inhaler. The propellant-free pharmaceutical formulation comprising: (a) active substances selected from aclidinium bromide and formoterol fumarate; (b) a solvent; and (c) a pharmacologically acceptable preservative, optionally including a pharmacologically acceptable stabilizer, a pharmacologically acceptable solubilizing agent, or other pharmacologically acceptable additives. 本发明公开一种液态、无推进剂药物制剂以及通过将药物制剂于吸入器雾化来施用药物制剂的方法。该液态、无推进剂的药物制剂,包括:(a)选自阿地溴铵、富马酸福莫特罗的活性物质;(b)溶剂;(c)药学上可接受的防腐剂,任选地包括药学上可接受的稳定剂、药学上可接受的增溶剂,药学上可接受的助溶剂或其它药学上可接受的添加剂。