Gene sequencing sensing device and signal processing method

A sensing device for gene sequencing of a sample comprises a CMOS image sensor, the surface of which is processed to be suitable for carrying a fluid sample, and a CMOS pixel array used for receiving and detecting optical signals emitted by the sample and generating corresponding detection signal output; the CMOS pixel is a dual-conversion gain pixel, has two different conversion gains, and comprises a high conversion gain HiCG and a low conversion gain LoCG, and the CMOS pixel can be in a high conversion gain mode and a low conversion gain mode. A group of pixel detection signals VH and VL are shot under the high conversion gain and the low conversion gain respectively, one signal is selected, all selected VH signal values are divided by the ratio G of the high conversion gain HiCG to the low conversion gain LoCG, and then the value and the selected VL signal are synthesized into a complete image signal. 一种用于对样本进行基因测序的传感装置，包括一个CMOS图像传感器，其表面处理成适合承载流体状样本，包括一个CMOS像素阵列，用于接受并检测所述样本发出的光信号，并产生相应的检测信号输出；所述CMOS像素为双转换