Curdlan/halloysite composite hydrogel as well as application and preparation method thereof

The invention discloses curdlan/halloysite composite hydrogel as well as application and a preparation method thereof. The existing polysaccharide gel has the problems of poor air permeability and slow release effect, and the toxicity is increased due to the fact that chemical auxiliaries are often...

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Bibliographische Detailangaben
Hauptverfasser: WANG LEI, SHOU ZHOUXIANG, JIN XIAOSHU, CHEN JIAJIA, CHEN XIAWEI, JI DAN, FEI YIWEN, XU HENG, SUN YAN, LI WEIDONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses curdlan/halloysite composite hydrogel as well as application and a preparation method thereof. The existing polysaccharide gel has the problems of poor air permeability and slow release effect, and the toxicity is increased due to the fact that chemical auxiliaries are often added in conventional modification. The curdlan/halloysite composite hydrogel disclosed by the invention has a porous structure, the used materials comprise curdlan and halloysite, and the carried drugs are aspirin and probucol. The curdlan/halloysite composite hydrogel with a good drug loading effect is formed under an alkaline condition by utilizing the unique gel forming characteristics of low-temperature reversibility and high-temperature irreversibility of curdlan and the three characteristics of forming a good dispersion system in water and good dissolution in an alkaline solution and combining the special tubular structure of halloysite. The materials used by the hydrogel material are all natural materials,