MICROORGANISMS AND METHOD FOR PRODUCING GLYCOLIC ACID FROM PENTOSES AND HEXOSES

The invention relates to a recombinant microorganism that exhibits (i) increased activity of conversion of D-ribulose-5-phosphate into D-arabinose-5-phosphate compared to the same non-modified microorganism; (ii) increased activity of catalysis of the cleavage of the D-arabinose-5-phosphate into D-glyceraldehyde-3- phosphate and glycolaldehyde compared to the same non-modified microorganism; (iii) increased activity of oxidation of the glycolaldehyde into glycolate compared to the same non-modified microorganism; and (iv) reduced activity of oxidation of the glyceraldehyde-3-phosphate into 1,3-bisphosphoglycerate compared to the same non-modified microorganism. The invention also relates to a method for producing glycolic acid from pentoses and/or hexoses using such a recombinant microorganism. The invention further relates to a method for producing glycolic acid involving a biomass production phase and a phase of bioconversion of the hexoses and/or pentoses into glycolic acid. 本发明涉及重组微生物，其展示出i)与其非修饰微生物相比，增加的