DETECTION OF TARGETS

Methods and cartridges for detecting targets are provided. A biological sample is introduced to a cartridge. Targets in the sample are photonically labeled with fluorescent particles in a first liquid layer in the cassette. Photonically-labeled targets are separated out of the sample into a second l...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BOWERS JAYSON L, CAPPILLINO MICHAEL, GITE SADANAND, STRAUS DON
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Methods and cartridges for detecting targets are provided. A biological sample is introduced to a cartridge. Targets in the sample are photonically labeled with fluorescent particles in a first liquid layer in the cassette. Photonically-labeled targets are separated out of the sample into a second liquid layer within the cassette, detected, and counted to show presence of the targets in the subject. Cartridges include a receiving reservoir, a mixing well for introducing the sample to photonic labels and magnetic particles, and an imaging well for detecting and counting targets from the sample. The sample may be a human stool sample. A filter may be used to filter particulates out of the sample. 提供了用于检测靶标的方法和筒。将生物样品引入到筒中。用盒中的第一液体层中的荧光粒子对该样品中的靶标进行光子标记。将光子标记的靶标从该样品中分离到该盒内的第二液体层中,检测并计数,以示出这些靶标在受试者中的存在。筒包含收容储器、用于将该样品引入到光子标记物和磁性粒子中的混合孔以及用于对来自该样品的靶标进行检测和计数的成像孔。该样品可以是人类粪便样品。过滤器可以用于过滤出该样品中的微粒。