Coronary artery endothelial cell angiogenesis promoter

The invention provides a coronary artery endothelial cell angiogenesis promoter, and belongs to the technical field of cardiac medicine. It is found through experiments that proliferation and angiogenesis of coronary artery endothelial cells can be effectively promoted by lowering RP11-71G12.1, and...

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Hauptverfasser: WEI JING, SU JINHUAN, LIU JINGXING, WANG YINGCUI, HUANG DONGSHUAI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a coronary artery endothelial cell angiogenesis promoter, and belongs to the technical field of cardiac medicine. It is found through experiments that proliferation and angiogenesis of coronary artery endothelial cells can be effectively promoted by lowering RP11-71G12.1, and therefore siRNA of RP11-71G12.1 can be used for preparing a medicine for treating ischemic heart disease, and a new treatment direction is provided for treating ischemic heart disease. 本发明提供了一种冠状动脉内皮细胞血管生成促进剂,属于心脏医学技术领域。本发明通过实验发现下调RP11-71G12.1能够有效的促进冠状动脉内皮细胞增殖和血管生成,因此可将RP11-71G12.1的siRNA用于制备治疗缺血性心脏病的药物,为治疗缺血性心脏病提供新的治疗方向。