Application of INK128 in preparation of product for delaying ovarian development
The invention discloses application of INK128 in preparation of a product for delaying ovarian development, and relates to the field of medicines. The product for delaying ovarian development is specifically a product for maintaining an ovarian endocrine function or a product for improving an ovaria...
Gespeichert in:
Hauptverfasser: | , , , , , , , |
---|---|
Format: | Patent |
Sprache: | chi ; eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | The invention discloses application of INK128 in preparation of a product for delaying ovarian development, and relates to the field of medicines. The product for delaying ovarian development is specifically a product for maintaining an ovarian endocrine function or a product for improving an ovarian mitochondrial function, and the ovarian is specifically a reconstructed ovarian; and it is found that after the INK128 is fed, the development of the reconstructed ovary is remarkably prolonged to 12 weeks, and meanwhile the endocrine function of the ovary is maintained to a certain degree. Meanwhile, an RNAseq result shows that compared with a reconstructed ovary groupobtained by not feeding the INK128 , after the INK128 is fed, an mTOR signal path is remarkably inhibited, related functions of mitochondria are remarkably improved, immune response and inflammatory response are remarkably reduced, and a crucial role is played in delaying ovarian senescence.
本发明公开一种INK128在制备延缓卵巢发育的产品中的应用,涉及医药领域;所述延缓卵巢发育的产品具体为维持卵巢内分 |
---|