Sustained-release levofloxacin eye drops as well as preparation method and application thereof

The invention discloses sustained-release levofloxacin eye drops as well as a preparation method and application thereof. According to the sustained-release levofloxacin eye drops as well as the preparation method and application thereof, the sustained-release levofloxacin eye drops are characterized by comprising the following components of 0.5%-1.5% (w/v) of levofloxacin, a thickening agent, an osmotic pressure regulator, a metal chelating agent, a bacteriostatic agent, a pH regulator and water for injection. According to the invention, the thickening agent such as hydroxypropyl methylcellulose or polyvinylpyrrolidone is used as an adhesive polymer, so that the retention time of the eye drops in the eyes is prolonged, the bioavailability of the eye drops in the eyes is improved, the administration frequency is reduced, and the patient compliance is improved. The eye drops are mainly used for blepharitis, hordeolum, dacryocystitis, conjunctivitis, meibomitis and keratitis and is used for sterile therapy in t