Method for preparing crude heparin sodium from sow intestines by biological enzyme method

The invention discloses a method for preparing crude heparin sodium from sow intestines by a biological enzyme method. The method comprises the following steps of intestinal mucosa extraction, enzymolysis, separation, cooling, adsorption, and resin collection and solidification. The separation effect between grease and protein can be improved, the production cost is reduced, the technology is mature and practical, the heparin yield is high, and the process quality is stable. 本发明公开了生物酶法利用母猪肠制备粗品肝素钠的方法。本发明中包括以下步骤：肠粘膜提取、酶解、分离、降温、吸附、树脂收集以及固化，本发明能够增加油脂与蛋白质之间的分离效果，降低生产成本，技术成熟、实用，肝素收率高，工艺品质稳定。