Preparation method of saflufenacil intermediate

The invention relates to the technical field of pesticide organic synthesis, and provides a saflufenacil intermediate preparation method, which comprises: a), carrying out reaction on 2-chloro-4-fluoro-5-aminobenzoate and ethyl 4,4,4-trifluoroacetoacetate to obtain an intermediate (1); b), reacting the intermediate (1) with methylamine hydrochloride to obtain an intermediate (2); and c), reactingthe intermediate (2) with an acylation reagent to obtain the 2-chlorine-4-fluorine-5-(3-methyl-2, 6-diketone-4-trifluoromethyl-2, 3-dihydropyrimidinyl-1(6H)- group) benzoate. The method solves the problems that toxic reagent raw materials with great harm are used in the existing saflufenacil intermediate reaction process, the operation is complicated, and the yield is not high. 本发明涉及农药有机合成技术领域，提供一种苯嘧磺草胺中间体的制备方法，包括如下步骤：a)将2-氯-4-氟-5-氨基苯甲酸酯与三氟乙酰乙酸乙酯反应得中间体(1)；b)将中间体(1)与甲胺盐酸盐反应得到中间体(2)；c)将中间体(2)与酰化试剂反应，得到2-氯-4-氟-5-(3-甲基-2,6-二酮-4-三氟甲基-2,3-二氢嘧啶基-1(6H)-基)苯甲酸酯。其解决现有的苯嘧磺草胺中间体反应过程使用危害性大的有毒试剂原料，操作繁琐以及收率不高的问题。