Quetiapine fumarate-containing tablet and preparation method thereof

The invention relates to a quetiapine fumarate-containing tablet and a preparation method thereof. The quetiapine fumarate-containing tablet or a tablet core thereof comprises quetiapine fumarate as an active component, internally added auxiliary materials and externally added auxiliary materials. The preparation method comprises the following steps of firstly crushing the active component, uniformly mixing the crushed active component with one or more internally added auxiliary materials, adding a wetting agent, carrying out primary granulation, drying obtained wet granules, crushing the granules, sieving the crushed granules with a 50-15-mesh sieve, uniformly mixing the sieved granules with the rest internally added auxiliary materials, adding the wetting agent again, carrying out secondary granulation, and drying and straightening wet granules obtained again; and then mixing the dried granules with the externally added auxiliary materials, and performing tabletting, wherein the internally added auxiliary m