Application of inhibitor of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity
The invention relates to the field of medicine, in particular to application of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity. The parvalbumin inhibitor is selected from a substance capable of being specifically combined with small albumin o...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LIN SHAOJIAN YUAN LING ZHANG ANKE LUAN BING |
| description | The invention relates to the field of medicine, in particular to application of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity. The parvalbumin inhibitor is selected from a substance capable of being specifically combined with small albumin or a substance capable of being specifically combined with a small albumin target. The parvalbumin inhibitor is selected from polypeptide, and the amino acid sequence of the polypeptide is shown as SEQ ID NO. 1. The inventor of the invention finds the function and action mechanism of the parvalbumininhibitor in obesity, inhibits the combination of the parvalbumin inhibitor and the colony stimulating factor 1 receptor by designing the synthetic polypeptide, and plays a role in reducing weight andimproving insulin tolerance, fatty liver and other symptoms caused by obesity in high-fat induced obesity mice. A new theoretical basis is laid for weight reduction and obesity-related disease treatment, and a new drug action |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN112472790A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN112472790A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN112472790A3</originalsourceid><addsrcrecordid>eNqNirEKwjAURbs4iPoPzw8QbBWKYymKk5N7eUle9UFNHkla6O6HG4s6O13OPWeePSuRjjVGdhZcC2zvrDg6_wZBP2Cn-gfbJEA8peeXinem1xHaFCc1kI1sb4DWQPSEEzhFgeM4nYYDYaAAGvtABtT41cts1mIXaPXZRbY-Ha_1eUPiGgqCmizFpr7kebEvi_KwrXb_NC_zIUty</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Application of inhibitor of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity</title><source>esp@cenet</source><creator>LIN SHAOJIAN ; YUAN LING ; ZHANG ANKE ; LUAN BING</creator><creatorcontrib>LIN SHAOJIAN ; YUAN LING ; ZHANG ANKE ; LUAN BING</creatorcontrib><description>The invention relates to the field of medicine, in particular to application of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity. The parvalbumin inhibitor is selected from a substance capable of being specifically combined with small albumin or a substance capable of being specifically combined with a small albumin target. The parvalbumin inhibitor is selected from polypeptide, and the amino acid sequence of the polypeptide is shown as SEQ ID NO. 1. The inventor of the invention finds the function and action mechanism of the parvalbumininhibitor in obesity, inhibits the combination of the parvalbumin inhibitor and the colony stimulating factor 1 receptor by designing the synthetic polypeptide, and plays a role in reducing weight andimproving insulin tolerance, fatty liver and other symptoms caused by obesity in high-fat induced obesity mice. A new theoretical basis is laid for weight reduction and obesity-related disease treatment, and a new drug action</description><language>chi ; eng</language><subject>FOODS OR FOODSTUFFS ; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210312&DB=EPODOC&CC=CN&NR=112472790A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210312&DB=EPODOC&CC=CN&NR=112472790A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIN SHAOJIAN</creatorcontrib><creatorcontrib>YUAN LING</creatorcontrib><creatorcontrib>ZHANG ANKE</creatorcontrib><creatorcontrib>LUAN BING</creatorcontrib><title>Application of inhibitor of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity</title><description>The invention relates to the field of medicine, in particular to application of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity. The parvalbumin inhibitor is selected from a substance capable of being specifically combined with small albumin or a substance capable of being specifically combined with a small albumin target. The parvalbumin inhibitor is selected from polypeptide, and the amino acid sequence of the polypeptide is shown as SEQ ID NO. 1. The inventor of the invention finds the function and action mechanism of the parvalbumininhibitor in obesity, inhibits the combination of the parvalbumin inhibitor and the colony stimulating factor 1 receptor by designing the synthetic polypeptide, and plays a role in reducing weight andimproving insulin tolerance, fatty liver and other symptoms caused by obesity in high-fat induced obesity mice. A new theoretical basis is laid for weight reduction and obesity-related disease treatment, and a new drug action</description><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNirEKwjAURbs4iPoPzw8QbBWKYymKk5N7eUle9UFNHkla6O6HG4s6O13OPWeePSuRjjVGdhZcC2zvrDg6_wZBP2Cn-gfbJEA8peeXinem1xHaFCc1kI1sb4DWQPSEEzhFgeM4nYYDYaAAGvtABtT41cts1mIXaPXZRbY-Ha_1eUPiGgqCmizFpr7kebEvi_KwrXb_NC_zIUty</recordid><startdate>20210312</startdate><enddate>20210312</enddate><creator>LIN SHAOJIAN</creator><creator>YUAN LING</creator><creator>ZHANG ANKE</creator><creator>LUAN BING</creator><scope>EVB</scope></search><sort><creationdate>20210312</creationdate><title>Application of inhibitor of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity</title><author>LIN SHAOJIAN ; YUAN LING ; ZHANG ANKE ; LUAN BING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN112472790A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2021</creationdate><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LIN SHAOJIAN</creatorcontrib><creatorcontrib>YUAN LING</creatorcontrib><creatorcontrib>ZHANG ANKE</creatorcontrib><creatorcontrib>LUAN BING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIN SHAOJIAN</au><au>YUAN LING</au><au>ZHANG ANKE</au><au>LUAN BING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Application of inhibitor of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity</title><date>2021-03-12</date><risdate>2021</risdate><abstract>The invention relates to the field of medicine, in particular to application of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity. The parvalbumin inhibitor is selected from a substance capable of being specifically combined with small albumin or a substance capable of being specifically combined with a small albumin target. The parvalbumin inhibitor is selected from polypeptide, and the amino acid sequence of the polypeptide is shown as SEQ ID NO. 1. The inventor of the invention finds the function and action mechanism of the parvalbumininhibitor in obesity, inhibits the combination of the parvalbumin inhibitor and the colony stimulating factor 1 receptor by designing the synthetic polypeptide, and plays a role in reducing weight andimproving insulin tolerance, fatty liver and other symptoms caused by obesity in high-fat induced obesity mice. A new theoretical basis is laid for weight reduction and obesity-related disease treatment, and a new drug action</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_CN112472790A |
| source | esp@cenet |
| subjects | FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
| title | Application of inhibitor of parvalbumin in preparation of product for preventing and treating obesity and diseases caused by obesity |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T02%3A57%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LIN%20SHAOJIAN&rft.date=2021-03-12&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN112472790A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |