Method and device for detecting genetic relationship
The invention discloses a method and a device for detecting a genetic relationship. The method comprises a gene chip detection step, an analysis site screening step, a site filtering step, a statistical analysis step and a genetic relationship judgment step. The gene chip detection step comprises th...
Gespeichert in:
Hauptverfasser: | , , |
---|---|
Format: | Patent |
Sprache: | chi ; eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | The invention discloses a method and a device for detecting a genetic relationship. The method comprises a gene chip detection step, an analysis site screening step, a site filtering step, a statistical analysis step and a genetic relationship judgment step. The gene chip detection step comprises the following steps: detecting genotype sites of free DNA of parents and females; the analysis site screening step comprises selecting sites of different homozygous genotypes of parents; the site filtering step comprises the step of filtering out sex chromosomes, mitochondria and undetected sites of parents or free DNA; the statistical analysis step comprises the steps of calculating a theta value, analyzing the theta value of each site of the free DNA, judging whether the site is heterozygous mutation or not, and calculating the proportion of the heterozygous mutation genotype site to the filtering sites; and the genetic relationship judgment step comprises comparing and judging the genetic relationship by using the |
---|