CARTRIDGE, ELECTROWETTING SAMPLE PROCESSING SYSTEM AND BEAD MANUPULATION METHOD

The invention concerns a cartridge (2), in particular a disposable cartridge, for use in an electrowetting sample processing system, wherein the cartridge comprises an internal gap (6) with at least one hydrophobic surface (17) for enabling an electrowetting induced movement of a microfluidic droplet (23) that comprises magnetic beads (52) and further comprises a bead accumulation zone (50), intowhich the microfluidic droplet is transferable by electrowetting force and in which the magnetic beads are exposable to a magnetic force of a bead manipulation magnet. The internal gap (6) comprises abead extraction opening (60) adjacent to the bead accumulation zone, wherein the bead extraction opening provides a passage from the gap to an exterior space of the cartridge and is configured to removably receive the bead manipulation magnet (62) for enabling an extraction of the magnetic beads from the microfluidic droplet by a removal of the bead manipulation magnet. This enables an efficientand reliable bead extractio