Crisaborole crystal form compound and preparation method thereof
The invention belongs to the technical field of medicine, and discloses a crisaborole crystal form compound and a preparation method thereof. The crisaborole crystal form compound displays characteristic diffraction peaks at 2[theta]+/-0.2 degree of 6.02 degrees, 12.04 degrees, 15.13 degrees, 15.35...
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Sprache: | chi ; eng |
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Zusammenfassung: | The invention belongs to the technical field of medicine, and discloses a crisaborole crystal form compound and a preparation method thereof. The crisaborole crystal form compound displays characteristic diffraction peaks at 2[theta]+/-0.2 degree of 6.02 degrees, 12.04 degrees, 15.13 degrees, 15.35 degrees, 18.09 degrees, 24.20 degrees and 26.08 degrees in an X-ray powder diffraction pattern, andthe X-ray powder diffraction pattern obtained through Cu-K alpha ray measurement is completely different from the prior art. According to the invention, the crisaborole crystal form compound has goodwater solubility and high stability, the preparation method is simple and easy to operate, the medication safety is greatly improved after the compound is prepared into a pharmaceutical composition, and the crisaborole crystal form compound is very suitable for clinical application.
本发明属于医药技术领域,公开了一种克立硼罗晶型化合物及其制备方法,其在2ϴ±0.2°衍射角表示的X-射线粉末衍射图谱在6.02°、12.04°、15.13、15.35、18.09、24.20和26.08处显示有特征衍射峰,使用Cu-Kα射线测量得到的X-射线粉末衍射谱图如图1所示,与 |
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