一种香叶木素(4-O-甲基)葡萄糖苷类化合物在制备降脂药物中的应用

本发明公开了一种香叶木素(4-O-甲基)葡萄糖苷类化合物作为降脂药物中的应用，在生物活性测试中，该化合物表现出下调或抑制小鼠3T3-L1前体脂肪细胞增殖和显著降低细胞分化过程中产生的脂质小滴数量，其苷元也具备，但该化合物效果更明显；与苷元相比，该化合物的水溶性显著增强，并且该化合物的转化率较高，具有更广泛的应用价值。 The invention discloses an application of a diosmetin(4-O-methyl) glucoside compound as a lipid-lowering drug; in a biological activity test, the compound shows down-regulation or inhibition of mouse3T3-L1 precursor adipocyte proliferation and significant reduction of the number of lipid droplets generated in a cell differentiation process, and aglycones of the diosmetin(4-O-methyl) glucoside compound also have the functions, but the effect of the compound is more obvious; compared with the aglycones, the compound has the advantages that the water solubility of the compound is remarkably enhanced, the conversion rate of the compound is high, and the compound has wider application value.