Method and kit for determining effectiveness of targeted drug apatinib

The invention discloses a method and a kit for determining effectiveness of a targeted drug apatinib. The method comprises the following steps: step 1, preparing a drug effect sample of the targeted drug apatinib; 2, carrying out DNA molecular marking on the drug effect sample obtained in the step 1...

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Hauptverfasser: ZHENG HUI, ZHU YANPING, XIE JIANBANG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a method and a kit for determining effectiveness of a targeted drug apatinib. The method comprises the following steps: step 1, preparing a drug effect sample of the targeted drug apatinib; 2, carrying out DNA molecular marking on the drug effect sample obtained in the step 1; 3, establishing a multiple linear regression mathematical model; 4, calculating the correlation coefficient of the effective variable of the drug effect of the targeted drug apatinib; and step 5, determining the effectiveness of the targeted drug apatinib according to the correlation coefficient of the effective variable of the drug effect. According to the method and the kit for determining the effectiveness of the targeted drug apatinib, provided by the invention, the efficacy effectivenessof the targeted drug apatinib is researched from a gene level in a DNA molecular marking manner, so that the efficacy degree of a drug scheme is associated with the expression of a gene, and the efficacy effectiveness of the