METHOD FOR PRODUCING HUMAN A1 ASTROCYTES, HUMAN A1 ASTROCYTES, AND METHOD FOR EVALUATING TEST SUBSTANCE

The present invention addresses the problem of providing: a method for producing human A1 astrocytes, said method comprising inducing human A1 astrocytes from human astrocytes other than human A1 astrocytes; the human A1 astrocytes obtained by the aforesaid method for producing human A1 astrocytes;...

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Bibliographische Detailangaben
Hauptverfasser:	SHIN WI-GYON, ENDOH SETSU, KOBAYASHI HAYATO, NABETANI AKIRA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention addresses the problem of providing: a method for producing human A1 astrocytes, said method comprising inducing human A1 astrocytes from human astrocytes other than human A1 astrocytes; the human A1 astrocytes obtained by the aforesaid method for producing human A1 astrocytes; and a method for evaluating a test substance using the aforesaid human A1 astrocytes. According to the present invention, a method for producing human A1 astrocytes, said method comprising step a for culturing human astrocytes other than human A1 astrocytes in the presence of TNFalpha and IFNgamma,is provided. 本发明的课题在于提供一种包括从除了人A1星形胶质细胞以外的人星形胶质细胞诱导人A1星形胶质细胞的人A1星形胶质细胞的制造方法；通过上述人A1星形胶质细胞的制造方法获得的人A1星形胶质细胞；及使用了人A1星形胶质细胞的被测物质的评价方法。根据本发明，可提供一种人A1星形胶质细胞的制造方法，其包括在TNFα及IFNγ的存在下培养除了人A1星形胶质细胞以外的人星形胶质细胞的工序a。