Artesunate granules and preparation method thereof

Artesunate granules and preparation method thereof

The invention provides artesunate granules and a preparation method thereof, and relates to the technical field of pharmaceutical preparations. The artesunate granules comprise the following components in parts by weight: 40-60 parts of artesunate, 850-950 parts of a filling agent, 50-250 parts of a...

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Hauptverfasser: LEI XIUFENG, ZHANG YANJUN, DAI XIAOHUA, WU JIAN, CHEN JUN, CHENG YAJUN
Format: Patent
Sprache:chi ; eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator LEI XIUFENG
ZHANG YANJUN
DAI XIAOHUA
WU JIAN
CHEN JUN
CHENG YAJUN
description The invention provides artesunate granules and a preparation method thereof, and relates to the technical field of pharmaceutical preparations. The artesunate granules comprise the following components in parts by weight: 40-60 parts of artesunate, 850-950 parts of a filling agent, 50-250 parts of a disintegrant and 1-5 parts of a corrective agent. The product can be rapidly dissolved at a low water temperature, the use convenience is improved, and the taste compliance is good. According to the invention, the preparation method is changed from a wet granulation to a dry granulation, and technological parameters of the dry granulation are optimized, which can improve the quality and yield of a finished product remarkably and shorten the production time, the product quality is stable and controllable through a quality research, and the clinical medication is safe and effective. The artesunate granules disclosed by the invention have rapid drug dissolution, high bioavailability, high production efficiency and is
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Artesunate granules and preparation method thereof
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