Artesunate granules and preparation method thereof
The invention provides artesunate granules and a preparation method thereof, and relates to the technical field of pharmaceutical preparations. The artesunate granules comprise the following components in parts by weight: 40-60 parts of artesunate, 850-950 parts of a filling agent, 50-250 parts of a...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides artesunate granules and a preparation method thereof, and relates to the technical field of pharmaceutical preparations. The artesunate granules comprise the following components in parts by weight: 40-60 parts of artesunate, 850-950 parts of a filling agent, 50-250 parts of a disintegrant and 1-5 parts of a corrective agent. The product can be rapidly dissolved at a low water temperature, the use convenience is improved, and the taste compliance is good. According to the invention, the preparation method is changed from a wet granulation to a dry granulation, and technological parameters of the dry granulation are optimized, which can improve the quality and yield of a finished product remarkably and shorten the production time, the product quality is stable and controllable through a quality research, and the clinical medication is safe and effective. The artesunate granules disclosed by the invention have rapid drug dissolution, high bioavailability, high production efficiency and is |
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