Application of polyphosphoinositide phosphatase 1 as target molecule

The invention discloses an application of MINPP1 as a target molecule in preparation of anti-HBV related hepatocellular carcinoma drugs. Growth and invasion of HBV related hepatocellular carcinoma cells are inhibited by overexpression or activation of the gene MINPP1. It is proved that the gene MINP...

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Bibliographische Detailangaben
Hauptverfasser:	BI KEFAN, JIANG JINGJING, CHEN WENBIAO, DIAO HONGYAN, ZHANG XUJUN, WANG KAIHANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention discloses an application of MINPP1 as a target molecule in preparation of anti-HBV related hepatocellular carcinoma drugs. Growth and invasion of HBV related hepatocellular carcinoma cells are inhibited by overexpression or activation of the gene MINPP1. It is proved that the gene MINPP1 can be used as an important target for effectively inhibiting proliferation of the HBV related hepatoma carcinoma cells. 本发明公开了一种MINPP1作为靶分子在制备用于抗HBV相关肝细胞癌药物中的应用，通过过表达或活化MINPP1基因抑制HBV相关肝癌细胞的生长和侵袭。本发明证实了MINPP1基因可以作为一种有效抑制HBV相关肝癌细胞增殖的重要靶点。