Novel carbamide peroxide preparation for preparing medicine for repairing pulmonary vascular injury and preparation method thereof

The invention relates to a preparation method of a novel carbamide peroxide preparation for preparing a medicine for repairing the pulmonary vascular injury. The preparation method comprises the stepsof: filling hydrogen peroxide and urea in a molar ratio of (1 to 2): 1 into a reactor, stirring at t...

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Hauptverfasser: YUAN PING, HUAI XU, MIAO YUQING, SUN YUANYUAN, LYU ZHENCHUN, WANG LAN, LIU JINMING, MENG XIANGRUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a preparation method of a novel carbamide peroxide preparation for preparing a medicine for repairing the pulmonary vascular injury. The preparation method comprises the stepsof: filling hydrogen peroxide and urea in a molar ratio of (1 to 2): 1 into a reactor, stirring at the room temperature to dissolve the hydrogen peroxide and the urea, then adding 0.05 to 0.2g of sorbic acid, and stirring at the room temperature for 30 to 200min so as to obtain reaction solution; and after the reaction is finished, carrying out cooling and crystallizing on the reaction solution at a temperature of 0 to 5 DEG C for crystallization time of 12 to 36h, then taking out the obtained product to filter, and freeze-drying a filter cake in a freeze dryer for drying time of 5 to 20h soas to obtain the product. The preparation method of the novel carbamide peroxide preparation, which is provided by the invention, is mild in reaction condition, higher in yield and simple in component, does not need to carry o