Application of MiR-29 sponge in preparation of medicine for treating type 2 diabetes mellitus

The invention discloses application of miR-29 sponge in preparation of a medicine for treating type 2 diabetes mellitus. The miR-29 sponge inhibits miR-29 in a targeting mode, the miR-29 sponge sealsexpression of miR-29 in macrophages or beta cells, and the miR-29 sponge is further applied to prepar...

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Bibliographische Detailangaben
Hauptverfasser:	SHI YING, SUN YI, YAO ZHENGJIAN, HAN XIAO, TANG WEI, ZHU YUNXIA, ZHOU YUNCAI, CHANG XIAO'AI, LI YATING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses application of miR-29 sponge in preparation of a medicine for treating type 2 diabetes mellitus. The miR-29 sponge inhibits miR-29 in a targeting mode, the miR-29 sponge sealsexpression of miR-29 in macrophages or beta cells, and the miR-29 sponge is further applied to preparation of the medicine for treating the type 2 diabetes mellitus, so that the problems of lack of treatment methods and treatment cost of the type 2 diabetes mellitus at present are solved. 本发明公开了miR-29海绵在制备用于治疗2型糖尿病的药物中的应用，所述miR-29海绵靶向抑制miR-29，该miR-29海绵封闭巨噬细胞或者β细胞中miR-29的表达，进一步将其应用于制备用于治疗2型糖尿病的药物中的应用，以解决2型糖尿病当前治疗方法匮乏以及治疗成本的问题。