MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDE FORMULATIONS AND METHODS FOR GASTROINTESTINAL TRACT-SPECIFIC DELIVERY

Disclosed are formulations, compositions and methods for delivery of melanocortin receptor-specific peptides, particularly cyclic peptides selective and specific for the melanocortin-1 receptor, to the lumen of the gastrointestinal tract for treatment of melanocortin receptor-mediated or responsive diseases, indications, conditions and syndromes of the gastrointestinal tract. 本文披露了用于将黑皮质素受体特异性肽、特别是对黑皮质素-1受体具有选择性和特异性的环状肽递送至胃肠道内腔，以治疗黑皮质素受体介导性或反应性胃肠道疾病、适应症、病症和综合征的配制品、组合物和方法。