Preparation method of SERS substrate of mesoporous SiO2@Ag material

The invention provides a preparation method of an SERS substrate of a mesoporous SiO2@Ag material, which comprises the steps of sequentially dissolving triethanolamine (TEA), cetyl ammonium bromide (CTAB), sodium salicylate and tetraethyl orthosilicate in deionized water through water bath heating to obtain a SiO2 solution, putting SiO2 powder obtained after centrifugal drying into a muffle furnace, carrying out high-temperature calcination to obtain a mesoporous SiO2 material with a uniform size, and obtaining the SERS substrate of the mesoporous SiO2@Ag composite material by regulating and controlling the use ratio of a solvent (deionized water) for dissolving silver nitrate to a solvent thermal (absolute ethyl alcohol) for dissolving polyvinylpyrrolidone and attaching nano Ag particlesto pore channels and the surface of the mesoporous SiO2 material through a hydrothermal method. According to the preparation method of the SERS substrate of the mesoporous SiO2@Ag material, the adsorption of noble metals is i