Preparation method of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide and medicinal application of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide
The invention discloses (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide as shown in a general formula (I), a preparation method of a compound, a new application of the compound and a pharmaceutical composition containing the compound in the aspect of inhibiting neuroglial cell inflammation. 本发明...
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| creator | LI HUI DENG ZHENG SHE ZHIHUA CAI PEI ZHENG YI WANG FANG MU YIBING |
| description | The invention discloses (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide as shown in a general formula (I), a preparation method of a compound, a new application of the compound and a pharmaceutical composition containing the compound in the aspect of inhibiting neuroglial cell inflammation.
本发明公开了一类(R)-1-烷烃酰基-2-取代吡咯烷-2-甲酰胺，如通式(I)所示，这类化合物的制备方法，这类化合物及含这类化合物的药物组合物在抑制神经小胶质细胞炎症方面的新应用。 |
| format | Patent |
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本发明公开了一类(R)-1-烷烃酰基-2-取代吡咯烷-2-甲酰胺，如通式(I)所示，这类化合物的制备方法，这类化合物及含这类化合物的药物组合物在抑制神经小胶质细胞炎症方面的新应用。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210105&DB=EPODOC&CC=CN&NR=112174870A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210105&DB=EPODOC&CC=CN&NR=112174870A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI HUI</creatorcontrib><creatorcontrib>DENG ZHENG</creatorcontrib><creatorcontrib>SHE ZHIHUA</creatorcontrib><creatorcontrib>CAI PEI</creatorcontrib><creatorcontrib>ZHENG YI</creatorcontrib><creatorcontrib>WANG FANG</creatorcontrib><creatorcontrib>MU YIBING</creatorcontrib><title>Preparation method of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide and medicinal application of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide</title><description>The invention discloses (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide as shown in a general formula (I), a preparation method of a compound, a new application of the compound and a pharmaceutical composition containing the compound in the aspect of inhibiting neuroglial cell inflammation.
本发明公开了一类(R)-1-烷烃酰基-2-取代吡咯烷-2-甲酰胺，如通式(I)所示，这类化合物的制备方法，这类化合物及含这类化合物的药物组合物在抑制神经小胶质细胞炎症方面的新应用。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqdzLEKwjAUheEsDqK-Q9x0CJhaqKsUxUlE3Ms1ucWLaW5I0qHv4sNa0AcQpzP8h28qXpeIASJkYi87zA-2klu5uq6VVuCe4HlwqlCpv6dMuc9oZRhiZEeWPI6l5dhBRxYleDsSlgx5cBJCcGQ-8J_iXExacAkX352J5fFwq08KAzeYAhj0mJv6rHWhq3JXbfbbXz5vym5Sag</recordid><startdate>20210105</startdate><enddate>20210105</enddate><creator>LI HUI</creator><creator>DENG ZHENG</creator><creator>SHE ZHIHUA</creator><creator>CAI PEI</creator><creator>ZHENG YI</creator><creator>WANG FANG</creator><creator>MU YIBING</creator><scope>EVB</scope></search><sort><creationdate>20210105</creationdate><title>Preparation method of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide and medicinal application of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide</title><author>LI HUI ; DENG ZHENG ; SHE ZHIHUA ; CAI PEI ; ZHENG YI ; WANG FANG ; MU YIBING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN112174870A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LI HUI</creatorcontrib><creatorcontrib>DENG ZHENG</creatorcontrib><creatorcontrib>SHE ZHIHUA</creatorcontrib><creatorcontrib>CAI PEI</creatorcontrib><creatorcontrib>ZHENG YI</creatorcontrib><creatorcontrib>WANG FANG</creatorcontrib><creatorcontrib>MU YIBING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LI HUI</au><au>DENG ZHENG</au><au>SHE ZHIHUA</au><au>CAI PEI</au><au>ZHENG YI</au><au>WANG FANG</au><au>MU YIBING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide and medicinal application of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide</title><date>2021-01-05</date><risdate>2021</risdate><abstract>The invention discloses (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide as shown in a general formula (I), a preparation method of a compound, a new application of the compound and a pharmaceutical composition containing the compound in the aspect of inhibiting neuroglial cell inflammation.
本发明公开了一类(R)-1-烷烃酰基-2-取代吡咯烷-2-甲酰胺，如通式(I)所示，这类化合物的制备方法，这类化合物及含这类化合物的药物组合物在抑制神经小胶质细胞炎症方面的新应用。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Preparation method of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide and medicinal application of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide |
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