Preparation method of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide and medicinal application of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide

Preparation method of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide and medicinal application of (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide

The invention discloses (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide as shown in a general formula (I), a preparation method of a compound, a new application of the compound and a pharmaceutical composition containing the compound in the aspect of inhibiting neuroglial cell inflammation. 本发明...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LI HUI, DENG ZHENG, SHE ZHIHUA, CAI PEI, ZHENG YI, WANG FANG, MU YIBING
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention discloses (R)-1-alkanoyl-2-substituted pyrrolidine-2-formamide as shown in a general formula (I), a preparation method of a compound, a new application of the compound and a pharmaceutical composition containing the compound in the aspect of inhibiting neuroglial cell inflammation. 本发明公开了一类(R)-1-烷烃酰基-2-取代吡咯烷-2-甲酰胺，如通式(I)所示，这类化合物的制备方法，这类化合物及含这类化合物的药物组合物在抑制神经小胶质细胞炎症方面的新应用。