EGFR and CDK4/6 small molecule targeted drug composition and application thereof

The invention relates to an EGFR and CDK4/6 small-molecule targeted drug composition and application thereof. The EGFR and CDK4/6 small-molecule targeted drug composition is composed of two targeted drugs of an EGFR small-molecule inhibitor and a CDK4/6 small-molecule inhibitor, wherein the EGFR sma...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LIN FAN, ZHOU XIAOHUI, YANG LIU, LIU XIAORONG, GONG YEQING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to an EGFR and CDK4/6 small-molecule targeted drug composition and application thereof. The EGFR and CDK4/6 small-molecule targeted drug composition is composed of two targeted drugs of an EGFR small-molecule inhibitor and a CDK4/6 small-molecule inhibitor, wherein the EGFR small-molecule inhibitor is Erlotinib, and the CDK4/6 small molecule inhibitor is Palbociclib. According to the EGFR and CDK4/6 small molecule targeted drug composition and the application thereof, the compatibility is reasonable, the medicine sensitivity of the EGFR small molecule inhibitor can be improved and the effect of the CDK4/6 small molecule inhibitor in the aspect of colorectal tumor resistance can be further exerted by the combination of the EGFR small molecule inhibitor and the CDK4/6 small molecule inhibitor, so that the treatment effect of the EGFR small molecule inhibitor is improved, experiments prove that the combined medication of the EGFR small-molecule inhibitor and the CDK4/6 small-molecule inhibi