Application of SRCAP ATPase inhibitor in colorectal cancer treatment

The invention provides an application of a reagent for detecting the activity of SRCAP ATPase or the expression level of a downstream transcription factor regulated and controlled by the SRCAP ATPasein preparation of a diagnostic agent/kit for diagnosing or prognosing colorectal cancer diseases of m...

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Bibliographische Detailangaben
Hauptverfasser:	QIAN GUOMIN, YANG LIULIU, LIU BENYU, YE BUQING, LI HUIMU, WANG YANYING, FAN ZUSEN, DU YING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides an application of a reagent for detecting the activity of SRCAP ATPase or the expression level of a downstream transcription factor regulated and controlled by the SRCAP ATPasein preparation of a diagnostic agent/kit for diagnosing or prognosing colorectal cancer diseases of mammals. The invention further provides an application of an inhibitor/antagonist of the activity ofthe SRCAP ATPase or the downstream transcription factor regulated and controlled by the SRCAP ATPase in preparation of a medicine/kit for preventing or treating the colorectal cancer diseases of themammals. 本发明提供用于检测SRCAP ATPase酶活性或其调控的下游转录因子的表达水平的试剂在制备用于诊断或预后哺乳动物的结直肠癌疾病的诊断剂/试剂盒中的应用。本发明还提供SRCAP ATPase酶活性或其调控的下游转录因子的抑制剂/拮抗剂在制备用于预防或治疗哺乳动物的结直肠癌疾病的药物/试剂盒中的应用。