Application of anaphalis virgata n-butyl alcohol extract

The invention relates to application of an anaphalis virgata n-butyl alcohol extract. The anaphalis virgata n-butyl alcohol extract is obtained from anaphalis virgata through 70% ethanol thermal extraction, and in-vitro cell experiments show that the anaphalis virgata n-butyl alcohol extract has the...

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Hauptverfasser: AJIAIKEBAIER AISA, MAI DINA, MAYINUER BAIKELI, NUOMONUOFU SUODIKE, HU MIAO, XIN XUELEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to application of an anaphalis virgata n-butyl alcohol extract. The anaphalis virgata n-butyl alcohol extract is obtained from anaphalis virgata through 70% ethanol thermal extraction, and in-vitro cell experiments show that the anaphalis virgata n-butyl alcohol extract has the effects of reducing blood sugar and relieving kidney lesions caused by high glucose injury. According to the extract, the glucose consumption of rat myoblasts (L6) and the Na - K - ATP enzymatic activity of a high-glucose induced high-glucose injured mouse kidney cell (MPC-5) model can be remarkably increased, and the effects of reducing blood sugar and regulating a polyol pathway to relieve kidney lesions caused by high-glucose injury are shown. 本发明涉及一种帚枝香青正丁醇提取物的用途,该帚枝香青正丁醇提取物是从帚枝香青中经过70%乙醇热提取得到,通过体外细胞实验表明该帚枝香青正丁醇提取物具有降血糖及改善高糖损伤引起的肾脏病变,它能显著增加大鼠成肌细胞(L6)对葡萄糖的消耗及高糖诱导的高糖损伤小鼠肾脏细胞(MPC-5)模型的Na+-K+-ATP酶活性,显示出其具有降血糖及调节多元醇通路从而改善高糖损伤引起的肾脏病变的作用。