LncRNA capable of serving as gastric cancer diagnostic marker and application of lncRNA

The invention discloses lncRNA capable of serving as a gastric cancer diagnosis marker and application of the lncRNA. A gastric cancer model is obtained by using MNNG modeling, lncRNA for expressing difference in the gastric cancer model is obtained by screening through a high-throughput sequencing...

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Hauptverfasser: CHEN XUAN, YU ZHIHONG, CHEN SISI, WU RENZHAO, REN ZEMING, LI YU, CHAI KEQUN, ZHU JIAJIE, FEI BAOYING, TONG YELING, XUE XIAOMIN
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creator CHEN XUAN
YU ZHIHONG
CHEN SISI
WU RENZHAO
REN ZEMING
LI YU
CHAI KEQUN
ZHU JIAJIE
FEI BAOYING
TONG YELING
XUE XIAOMIN
description The invention discloses lncRNA capable of serving as a gastric cancer diagnosis marker and application of the lncRNA. A gastric cancer model is obtained by using MNNG modeling, lncRNA for expressing difference in the gastric cancer model is obtained by screening through a high-throughput sequencing technology, and finally the lncRNA SC1 is screened out. The lncRNA SC1 provided by the invention isused as an MNNG induced rat gastric cancer diagnosis marker, the lncRNA SC1 can be used for accurately identifying an MNNG induced rat gastric cancer model due to its good specificity, the lncRNA SC1can detect MNNG-induced rat cancer due to its high sensitivity, the lncRNA SC1 provides a new detection means for diagnosing MNNG-induced rat gastric cancer due to its high diagnosis efficiency and guaranteed reliability, a detection method is simple and easy to implement, and the lncRNA SC1 has good transformation medical prospect potential. 本发明公开了一种可作为胃癌诊断标志物的lncRNA及其应用。本发明通过使用MNNG造模获得胃癌模型,再通过高通量测序技术筛选获得在胃癌模型中表达差异的lncRNA
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The lncRNA SC1 provided by the invention isused as an MNNG induced rat gastric cancer diagnosis marker, the lncRNA SC1 can be used for accurately identifying an MNNG induced rat gastric cancer model due to its good specificity, the lncRNA SC1can detect MNNG-induced rat cancer due to its high sensitivity, the lncRNA SC1 provides a new detection means for diagnosing MNNG-induced rat gastric cancer due to its high diagnosis efficiency and guaranteed reliability, a detection method is simple and easy to implement, and the lncRNA SC1 has good transformation medical prospect potential. 本发明公开了一种可作为胃癌诊断标志物的lncRNA及其应用。本发明通过使用MNNG造模获得胃癌模型,再通过高通量测序技术筛选获得在胃癌模型中表达差异的lncRNA</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20201229&amp;DB=EPODOC&amp;CC=CN&amp;NR=112143808A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20201229&amp;DB=EPODOC&amp;CC=CN&amp;NR=112143808A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN XUAN</creatorcontrib><creatorcontrib>YU ZHIHONG</creatorcontrib><creatorcontrib>CHEN SISI</creatorcontrib><creatorcontrib>WU RENZHAO</creatorcontrib><creatorcontrib>REN ZEMING</creatorcontrib><creatorcontrib>LI YU</creatorcontrib><creatorcontrib>CHAI KEQUN</creatorcontrib><creatorcontrib>ZHU JIAJIE</creatorcontrib><creatorcontrib>FEI BAOYING</creatorcontrib><creatorcontrib>TONG YELING</creatorcontrib><creatorcontrib>XUE XIAOMIN</creatorcontrib><title>LncRNA capable of serving as gastric cancer diagnostic marker and application of lncRNA</title><description>The invention discloses lncRNA capable of serving as a gastric cancer diagnosis marker and application of the lncRNA. 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A gastric cancer model is obtained by using MNNG modeling, lncRNA for expressing difference in the gastric cancer model is obtained by screening through a high-throughput sequencing technology, and finally the lncRNA SC1 is screened out. The lncRNA SC1 provided by the invention isused as an MNNG induced rat gastric cancer diagnosis marker, the lncRNA SC1 can be used for accurately identifying an MNNG induced rat gastric cancer model due to its good specificity, the lncRNA SC1can detect MNNG-induced rat cancer due to its high sensitivity, the lncRNA SC1 provides a new detection means for diagnosing MNNG-induced rat gastric cancer due to its high diagnosis efficiency and guaranteed reliability, a detection method is simple and easy to implement, and the lncRNA SC1 has good transformation medical prospect potential. 本发明公开了一种可作为胃癌诊断标志物的lncRNA及其应用。本发明通过使用MNNG造模获得胃癌模型,再通过高通量测序技术筛选获得在胃癌模型中表达差异的lncRNA</abstract><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title LncRNA capable of serving as gastric cancer diagnostic marker and application of lncRNA
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