LncRNA capable of serving as gastric cancer diagnostic marker and application of lncRNA

The invention discloses lncRNA capable of serving as a gastric cancer diagnosis marker and application of the lncRNA. A gastric cancer model is obtained by using MNNG modeling, lncRNA for expressing difference in the gastric cancer model is obtained by screening through a high-throughput sequencing...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	CHEN XUAN, YU ZHIHONG, CHEN SISI, WU RENZHAO, REN ZEMING, LI YU, CHAI KEQUN, ZHU JIAJIE, FEI BAOYING, TONG YELING, XUE XIAOMIN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention discloses lncRNA capable of serving as a gastric cancer diagnosis marker and application of the lncRNA. A gastric cancer model is obtained by using MNNG modeling, lncRNA for expressing difference in the gastric cancer model is obtained by screening through a high-throughput sequencing technology, and finally the lncRNA SC1 is screened out. The lncRNA SC1 provided by the invention isused as an MNNG induced rat gastric cancer diagnosis marker, the lncRNA SC1 can be used for accurately identifying an MNNG induced rat gastric cancer model due to its good specificity, the lncRNA SC1can detect MNNG-induced rat cancer due to its high sensitivity, the lncRNA SC1 provides a new detection means for diagnosing MNNG-induced rat gastric cancer due to its high diagnosis efficiency and guaranteed reliability, a detection method is simple and easy to implement, and the lncRNA SC1 has good transformation medical prospect potential. 本发明公开了一种可作为胃癌诊断标志物的lncRNA及其应用。本发明通过使用MNNG造模获得胃癌模型，再通过高通量测序技术筛选获得在胃癌模型中表达差异的lncRNA