Application of solanum nigrum or solanum nigrum extract to increasing sensitivity of antibiotics or antitumor drugs

The invention relates to an application of solanum nigrum or a solanum nigrum extract to increasing sensitivity of antibiotics or antitumor drugs, and belongs to the technical field of drugs. Throughresearches, the inventor finds that the solanum nigrum or the solanum nigrum extract is combined with the antibiotics or the antitumor drugs for use, so that the sensitivity of the antibiotics or theantitumor drugs can be improved, the dosage can be reduced, the using safety of the drugs can be improved, and the treatment time can be prolonged. A pharmaceutical composition can intervene in DNA abnormal methylation and histone modification mechanisms based on the solanum nigrum or the solanum nigrum extract, and can be used for treating drug resistance generated by the antibiotics or the antitumor drugs. According to the invention, a new solution is provided for the drug resistance of the existing antibiotics or the antitumor drugs, the life cycle of the existing drugs is fully utilized and prolonged, and the curre