miRNA related to colorectal cancer and application thereof

The invention belongs to the field of nucleic acid diagnosis and treatment, and particularly relates to miRNA related to colorectal cancer and application thereof. The miRNA related to colorectal cancer is miR-1290. The invention provides application of the miR-1290 in preparing a kit for distinguishing a colorectal cancer sample and a rectal cancer sample from a normal sample in a blood sample ofa subject. The invention determines that the miR-1290 is a miRNA diagnostic marker related to colorectal cancer for the first time, and establishes a novel colorectal cancer and rectal cancer tumor progression detection index. On the basis, the invention provides novel application of the miR-1290 in the aspect of initial diagnosis and rapid detection of colorectal cancer and rectal cancer and a related universal applicable kit. 本发明属于核酸诊断治疗领域，具体涉及一种与结肠癌和直肠癌相关的miRNA及其应用。本发明所述的与结肠癌和直肠癌相关的miRNA是miR-1290。本发明提供了miR-1290用于制备在受试者的血液样本中区分结肠癌样本和直肠癌样本与正常样本的试剂盒的用途。本发明首次确定了miR-1290是与结肠癌和直肠癌相关的miRNA诊断标记物，建立了新型的结肠癌和直肠癌肿瘤进展检测指标。在此基础