DOWNSTREAM PROCESSING OF AN ALKALINE PHOSPHATASE

The invention relates to the field of downstream processing (DSP) of an alkaline phosphatase (AP). More specifically, it relates to a method for reducing host cell protein content in a composition comprising AP. The invention further relates to a composition comprising an AP and a reduced content of...

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Hauptverfasser: JONK LUIGI JOHANNES CORNELIUS, CONNER STEPHEN EDWARD, KELLY TIMOTHY MARTIN, VAN DEN BERG ERIK JAN, HORNE HEATHER BETHEA, VAN ELSAS ANDREA, RAMAROSON MIALY FANJAMALALA, SHUKLA ABHINAV ALOK, COOK SUSAN, DOWLING VICTORIA ANNE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the field of downstream processing (DSP) of an alkaline phosphatase (AP). More specifically, it relates to a method for reducing host cell protein content in a composition comprising AP. The invention further relates to a composition comprising an AP and a reduced content of a host cell protein. 本发明涉及碱性磷酸酶(AP)的下游处理(DSP)领域。更具体地,本发明涉及减少包含AP的组合物中宿主细胞蛋白含量的方法。本发明进一步涉及包含AP和减少含量的宿主细胞蛋白的组合物。