Cell screening method and device based on convolutional neural network

The invention relates to a cell screening method and a device based on a convolutional neural network. The method comprises the steps that acquiring to-be-detected cell grey-scale maps corresponding to a plurality of to-be-detected cells in a cell culture pool; inputting a plurality of to-be-detecte...

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Bibliographische Detailangaben
Hauptverfasser: LIANG GUOLONG, HOU YUANYUAN, CHEN LIANG, MAIMAITIYIMING HASIMU, HAN XIAOJIAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a cell screening method and a device based on a convolutional neural network. The method comprises the steps that acquiring to-be-detected cell grey-scale maps corresponding to a plurality of to-be-detected cells in a cell culture pool; inputting a plurality of to-be-detected cell grey-scale maps corresponding to a plurality of to-be-detected cells into a target convolutional neural network model; according to the output of the target convolutional neural network model, obtaining protein expression quantities respectively corresponding to the plurality of cells to be detected; determing the target cells with the protein expression quantities meeting the set conditions from the plurality of to-be-detected cells according to the protein expression quantities corresponding to the plurality of to-be-detected cells, so that the cells with the high protein expression quantities are rapidly determined, the situation that cell screening can be performed only after repeated culture and screeni