Recombinant escherichia coli for producing gastrodin, construction method and application

The invention discloses recombinant escherichia coli for producing gastrodin, a construction method and application. The recombinant escherichia coli for producing gastrodin is characterized by comprising exogenous genes: a 4CL gene, a CCR gene, a CAR gene, an Sfp gene and an ugt73b6 gene. According to the invention, in a de novo synthesis pathway of gastrodin by taking glucose as the raw material microorganism, a coenzyme A dependent reduction pathway is introduced for the first time; an escherichia coli recombinant strain for catalytically synthesizing gastrodin is constructed; the yield of the escherichia coli recombinant strain is higher than that of recombinant escherichia coli and application for producing p-hydroxybenzyl alcohol or gastrodin by utilizing glucose in existing related patents (the patent application number: 20150264006.4); and the gastrodin yield in the invention reaches 292 mg/L. 本发明公开了一种生产天麻素的重组大肠杆菌、构建方法及应用，生产天麻素的重组大肠杆菌，其特征在于包括外源基因：4CL基因、CCR基因、CAR基因、Sfp基因和ugt73b6MKFA基因。本发明在以葡萄糖为原料微生物从头合